Cannabidiol, also known as CBD oil, is a non-psychoactive chemical compound that is commonly extracted from hemp. Research and anecdotes suggest benefits Learn more about medical marijuana use for those with lupus.
CBD Oil (Cannabidiol) and Lupus
Online, there are thousands of anecdotes speaking to the benefits of CBD oil. But, what is it, and how can it help reduce lupus symptoms?
Before diving in on the research on CBD oil, we will start with the recent regulatory changes. The perspective of the United States’ government has shifted in the last 12 months due to new rulings and legislation.
NOTE: The following is a review of regulatory changes in the United States only. Always be sure of the legal status of any products you buy or use.
Is CBD oil legal to buy?
The United States Food and Drug Administration (FDA) approved the first-ever, marijuana-derived pharmaceutical drug on June 25, 2018. Epidiolex, derived from CBD, was approved for the treatment of two pediatric seizure disorders .
Following the announcement by the FDA, the United States Drug Enforcement Agency released their own statement which classified Epidiolex in schedule V of the Controlled Substance Act. Per the law, drugs are classified into 5 different categories (schedules) “depending upon the drug’s acceptable medical use and the drugs’ abuse or dependency potential.” Schedule I contains drugs considered to have no medical benefit (e.g., heroin, LSD, methaqualone, marijuana). In contrast, schedule V contains drugs with very low potential for abuse (e.g., cough syrups with low amounts of codeine, antidiarrheals).
The passage of the legislation resulted in a statement from Scott Gottlieb, M.D., the commissioner of the FDA. Gottlieb noted that the FDA still considers CBD a drug and, as such, it is illegal to put into foods/health products without approval from the FDA.
What does this all mean?
While there are pathways for approval now, most products currently on the shelves are not compliant with the regulations. A CBD oil product is de-scheduled so long as it was produced using legal hemp and does not make improper health claims. As pilot programs from the 2014 Farm Bill make it to market, and states adopt the changes of the 2018 Farm Bill, there will be an increase in these products.
Looking for more information? NORML provides information on the status of marijuana (both recreational and medical), hemp, and medical CBD for every state.
Okay… so what is CBD oil?
Cannabidiol , also known as CBD, is one of the extracts of the cannabis and hemp plants ( Cannabis sativa ) that is under research for its use in chronic diseases. Commonly taken from the hemp plant, CBD is a non-psychoactive chemical compound. CBD is different from Tetrahydrocannabinol (THC), the compound in cannabis associated with the “high.” Products can contain CBD alone or CBD with THC.
Because it does not cause a “high,” CBD extracts may provide relief without inhibiting a person.
CBD oil can come in a range of forms including:
- liquid drops or tinctures
- chewing gum
- cooking oils
- edibles (gummies, brownies)
- eLiquid or vape cartridges
- salves or balms
Dosage, time until onset, and duration of effects vary by method. Be sure to read labels closely!
Cannabinoids, the many chemical compounds that make up cannabis, are found naturally in the body. Through these body systems, medical cannabis may help regulate the sensations of pain and pleasure, the processes of thinking and memory, body movement, the awareness of time, and appetite regulations.
According to the World Health Organization (WHO) studies show that CBD has some antioxidant, anti-inflammatory, and immune-system regulating effects . CBD may also change how the brain responds to pain , making it feel less intense and reducing the need for pain medication. This gives it a lot of potential use for people with lupus.
CBD oil & lupus
Studies on cannabis have found potential for using CBD oil as a way to reduce lupus symptoms. Many of these studies are conducted with small numbers of participants or rely on anecdotal reports . However, the research is beginning to paint a compelling picture regarding the efficacy of CBD.
A 2010 review published by the HHS government agency details the effects that cannabinoids have on the body . CBD goes directly to the immune cells and cause weak or damaged cells to die off. They also suppress T-cell responses, a major source of inflammation. This weakens the immune response, protecting cells from being attacked by the overactive immune systems of people with lupus. A 2015 report published in the Journal of the American Medical Association (JAMA) that looks specifically at multiple sclerosis implies that CBD may also directly protect nerve cells from autoimmune damage.
They interfere with a particular cytokine called IL-6, which is associated with inflammation-related tissue damage and joint pain . CBD has also been tested in experimental mouse models for many autoimmune disorders, and are being moved to testing in human models.
There are many clinical trials in the works on how CBD oil might help with inflammation. For now, though, we have a plant extract with a high potential to help and a low potential for habit formation and side effects. As interest – and funding — increases for using CBD oil to treat autoimmune diseases, this evidence will come.
Things to consider
Just like with medications, it is possible to have interaction effects between medications and CBD. Be sure to talk to your lupus treatment team about any potential interactions before starting any new treatments.
Also, any smokable products provide additional risks. The smoke can damage lung tissue, increase cancer risks, and contribute to inflammation. Only get your CBD oil from a reputable distributor.
If you do use CBD oil, you should also be vigilant and make sure that it doesn’t trigger a symptom flare. Though CBD has an immune system suppressing effect, you may have an allergy or be sensitive to the cannabinoid. In general, CBD is traditionally well tolerated with a good safety profile.
If you’re looking at products, be wary of overstated claims for health benefits. While the research is promising, individual products have likely not been validated via a clinical trial. And, keep your eyes out for new research.
13 thoughts on “ CBD Oil (Cannabidiol) and Lupus ”
I’ve tried a couple of CBD oils with no luck. I have wasted big bucks and have been let down. It didn’t do a thing for me. Sorry.
Thanks for sharing your experience with CBD oil. It’s great to hear from both sides on treatments that are available over-the-counter and are not deeply researched!
Me either. It is so not cheap by any means!
Give Haleigh’s Hope a go. Very reputable and great reviews. Don’t give up searching! https://haleighshope.com/
How do you get into the study
After 13 months of taking CBD Oil, I am in remissions from multiple autoimmune and connective tissue diseases. It’s a miracle in a bottle.
Where do you get your CBD oil?
Out of sheer agony I tried CBD oil tincture to help with the ongoing pains of lupus and RA complicated by allodynia from a recent spinal surgery that didn’t go as planned. To my amazement I have much less pain all over! I am a retired RN Asst Professor and did plenty of research before taking the leap of faith. My Internist approved it and I have decreased the Ultram by half in the past week. It is too expensive though but I think prices will drop as it becomes more popular.
I have been using CBD Crude Oil from hemp. Very high% of CBD, 0% THC. It has helped with my Lupus, chronic pain, anxiety and other additional autoimmune disorders. It is from a known, registered, regulated, independent lab tested Hemp oil producer so I trust the product I get.
Hi Betty my sister is suffering from lupus. Where do you get your CBD oil?
I’m using full spectrum CBD oil for lupus symptoms and it’s been helping me very much…I highly recommend it!
Hi Suzanne my sister is suffering from lupus. Where do you get your CBD oil?
You have to speak to someone for good explanation on dosage and just knowledge about cbd I lost money because I didn’t get the right info on strength,I’m fighting a connective tissue illness.as well as ostioporosis,r.a. as well .
Q&A: medical marijuana (cannabis) and lupus
Medical marijuana is not approved by the U.S. Food and Drug Administration (FDA) to treat lupus or any other condition.
There’s a great deal that we don’t know about whether medical marijuana can help people with lupus. Research is just starting to study how it might help manage or treat lupus.
Here’s what you need to know about medical marijuana.
What is medical marijuana?
The term “medical marijuana” refers to the use of the marijuana plant or herb, also known as cannabis, to treat symptoms of illness and other conditions. People have used the marijuana plant or its extracts for medical purposes for thousands of years. However, there hasn’t been enough research on how marijuana affects people to prove that medical marijuana is safe and effective.
Marijuana contains active chemicals called “cannabinoids.” The main cannabinoid is commonly known as THC, which gives users a “high.” Another often used cannabinoid is known as CBD, which doesn’t produce a high and may relieve pain and inflammation. There are also hundreds of synthetic cannabinoid chemicals – chemicals that are created in the laboratory that mimic natural cannabinoids.
Products that contain natural or synthetic THC or CBD come in many forms. These include the dried plant (herb or flower), edibles (brownies, cookies, candy), drinkables (coffee, tea, lemonade, soda), oils, tinctures (which are taken orally), sprays, and topical creams and gels.
What is medical marijuana used for?
People have used medical marijuana for a variety of health conditions. But the FDA hasn’t approved medical marijuana as a safe and effective treatment for lupus – or for any medical condition or symptoms.
The FDA has approved one drug that contains CBD to treat seizures associated with two severe forms of childhood epilepsy. It has also approved three medications containing synthetic cannabinoids that may help treat cancer symptoms or the side effects of cancer therapies.
The research for medical marijuana uses have steadily increased. That research suggests that medical marijuana may be helpful in these conditions and symptoms:
- pain and inflammation
- epileptic seizures
- diseases that affect the immune system, like HIV/AIDS and multiple sclerosis (MS)
- substance use disorders
- mental illnesses
Has medical marijuana been studied in people with lupus?
There is only one currently ongoing study of medical marijuana for lupus. That study is looking at whether a potential new drug made from a synthetic cannabinoid can treat joint pain and swelling (inflammation) in people with lupus. The drug, which is called JBT-101 (lenabasum), doesn’t produce a high. Several smaller studies of other conditions involving the immune system have reported positive results with lenabasum.
Until more research is done, we don’t know if medical marijuana can help people with lupus. We don’t know whether it can provide relief from lupus symptoms, if it interacts with drugs used to treat these symptoms, or whether it can lessen the side effects of those drugs.
What should people with lupus do if they’re considering using medical marijuana?
If someone with lupus is thinking about trying any alternative treatments or products – including medical marijuana – they should always talk with their doctor first. Some of these products might not be safe, may interact with medications, or could make symptoms worse.